Citicoline (CDP-Choline)

ADHD Relevant

Mechanism of Action:

  • Precursor to acetylcholine
  • Enhances phospholipid synthesis in neuronal membranes
  • Increases cerebral blood flow
  • Has neuroprotective properties
  • May enhance dopaminergic neurotransmission

Benefits:

  • Improves memory and cognitive function
  • Potentially beneficial for stroke recovery
  • May help with age-related cognitive decline
  • Could improve attention and focus

ADHD Benefits:

  • May improve attention and mental energy

Evidence Quality: Moderate - several clinical studies

Recommended Dosage:

250-1000 mg daily, divided into 2 doses

Side Effects:

  • Generally well-tolerated
  • May include mild gastrointestinal disturbances and headache

Research Evidence:

Several clinical studies support benefits for attention and mental energy.